US Route 180 (US 180) is an east–west US highway in northeastern Arizona and southern New Mexico in American Truck Simulator. The route is separated into four sections: The first section runs from SR 64 in Grand Canyon Village to SR 77 in Holbrook. The second section runs from SR 61 in St. Johns to US 60 and US 191 in Springerville. The third section runs from Interstate 10 in Deming to Interstate 25 in Las Cruces, entirely concurrent with Interstate 10. The fourth section runs from US 285 in Carlsbad to NM 218 in Hobbs, entirely concurrent with US 62.
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 Arizona
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| Cities | Camp Verde - Clifton - Ehrenberg - Flagstaff - Grand Canyon Village - Holbrook - Kayenta - Kingman - Nogales - Page - Phoenix - San Simon - Show Low - Sierra Vista - Tucson - Yuma |
| Highways | Interstate 8 - Interstate 10 (Business routes) - Interstate 15 - Interstate 17 - Interstate 19 - Interstate 40 (Business routes) US 60 - US 64 - US 70 - US 89 - US 89A - US 93 - US 95 - US 160 - US 163 - US 180 - US 191 SR 51 - SR 61 - SR 64 - SR 66 - SR 77 - SR 85 - SR 89 - SR 90 - SR 92 - SR 98 - SR 260 - SR 303 - SR 389 |
| See also | List of landmarks in Arizona - List of Truck Stops in Arizona |
 New Mexico
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| Cities | Alamogordo - Albuquerque - Artesia - Carlsbad - Clovis - Farmington - Gallup - Hobbs - Las Cruces - Raton - Roswell - Santa Fe - Socorro - Tucumcari |
| Highways | Interstate 10 - Interstate 25 - Interstate 40 US 54 - US 60 - US 62 - US 64 - US 70 - US 82 - US 84 - US 87 - US 160 - US 180 - US 285 - US 380 - US 412 - US 491 - US 550 NM 18 - NM 104 - NM 209 - NM 218 - NM 237 - NM 292 - NM 348 - NM 418 - NM 529 - NM 597 - NM 599 |
| See also | List of landmarks in New Mexico - List of Truck Stops in New Mexico |