Odense straddles the , which runs east-west in the vicinity, and runs on bridges at both sides. Specifically, the Great Belt Fixed Link, part of the connection towards Sweden, is the crossing east of the city.
- Twin-cities of Odense, which are also featured in SCS Software games:
|Cities||Aalborg - Esbjerg - Frederikshavn - Gedser - Hirtshals - København - Odense|
|Highways||E20 - E39 - E45 - E47 - E55|