The landmarks which truckers can visit in Eureka are a church, the Humboldt Bay and the Mad River.
To the north of the city, there is a Darchelle Uzau vineyard.
Eureka is connected to other cities by the and the . US 101 runs to Ukiah and San Francisco to the south and Crescent City and Coos Bay, Oregon to the north. SR 299 runs from US 101 on the north side of the city to the Darchelle Uzau vineyard and Redding to the east.