There are various European roads numbered A16 appearing in Euro Truck Simulator (ETS 1), Euro Truck Simulator 2 (ETS 2) or related games. The following list describes their existence in the game(s).
| Country | Road | Game | Nearby Cities |
|---|---|---|---|
| France | Autoroute 
|
ETS 2 | Calais, Paris |
| Italy | Autostrada 
|
ETS 2 (Italia) | Bari, Napoli |
| Lithuania | Magistralinis kelias 
|
ETS 2 (Beyond the Baltic Sea) | Vilnius |
| Netherlands | Autosnelweg 
|
ETS 2 | Rotterdam |